mafiamuslim: PDB

Bismillahirrahmanirrahim...

Assalamualaikum dear readers!

Alhamdulillah, we have finished our last quiz for this semester and it is pretty terrible for us. But, it doesn't mean we will fail this subject. We will prove that nothing is impossible, the word impossible itself say that "I'm-possible".

So today, we will explain to you about something unrelated to our course but useful as it is applicable in our daily lives.

PROTEIN DATA BANK

A repository for three-dimensional biological macro-molecular structure, that is submitted by biologists and biochemists from around the world such as proteins and nucleic acids. It is obtained by X-ray crystallography (80%) or NMR spectroscopy (16%).

The PDB is a key resource in areas of structural biology such as structural genomics.

HISTORY

It is founded in 1971 by Brookhaven National Laboratory, New York. The first set of data were entered on punched cards but later magnetic tapes. It is transferred to the Research Collaborators for Structural Bioinformatics (RCSB) in 1998.

mmCIF

Before mmCIF was evolved in the late 1990's to contain the coordinates and related information, PDB file format was used. It conforms to well-documented standards and facilitates automated data management. Its dictionary contains 2500 definitions for terms used to describe the crystallographic experiment.

mmCIF is an abbreviation of macro-molecular Crystallographic Information File.

EXAMPLES OF PROTEINS

Taka Amylase